Figure A-28. Number and Fold Growth of ASD Primary Research Publications from 2000 to 2010. Line graph and bar graph. On the line graph at the top left, there are seven lines, corresponding to the seven critical question areas of the IACC strategic plan. The y-axis is labeled ASD primary research publication count by year. The x-axis displays years from 2000 to 2010. The total number of primary research publications per year for all critical question categories increased each year. The category with the largest number of primary publications in 2010 was Biology, starting at 117 in the year 2000 and ending at 642 in the year 2000. The next largest category in 2010 is the Treatments and Interventions category, starting at 61 in the year 2000 and ending at 320 in the year 2000. Next is the Risk Factors category, starting at 71 in the year 2000 and ending at 284 in the year 2000. The fourth largest category is Diagnosis, starting at 46 publications in the year 2000 and ending with 178 in the year 2010. Next, the Services category started at 21 publications in the year 2000 and ended at 161 in the year 2000. Next is the Lifespan Issues category, starting at 10 in the year 2000 and ending at 64 in the year 2000. The seventh and last category is Infrastructure and Surveillance, which started at 5 publications in the year 2000 and ended at 43 publications in the year 2000. Below the line graph is a bar graph which displays the fold growth values in annual primary research publication output between the years 2000 and 2010 for the seven critical question categories. The highest fold growth value belongs to Infrastructure and Surveillance at 8 point 6. The next highest is seen in the Services category at seven point seven. Lifespan Issues had the third highest fold growth value at six point four. Next is the category of Biology, which grew five point five fold. The fifth highest fold growth value belongs to Treatments and Interventions at five point two. Sixth is Risk Factors, which grew four fold, and last is Diagnosis, which grew three point nine fold in annual primary research publication output from the years 2000 to 2010.