Strategic Plan Objective Detail
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Question 3: Short-term Objective A  

$13,926,663.00
Fiscal Year: 2009

Green dot: Objective has greater than or equal to the recommended funding.3SA. Coordinate and implement the inclusion of approximately 20,000 subjects for genome-wide association studies, as well as a sample of 1,200 for sequencing studies to examine more than 50 candidate genes by 2011. Studies should investigate factors contributing to phenotypic variation across individuals that share an identified genetic variant and stratify subjects according to behavioral, cognitive, and clinical features. IACC Recommended Budget: $43,700,000 over 4 years.

Download 2009 Question 3: Short-term Objective A projects (EXCEL)
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Project Title Principal Investigator Institution
1/5-Elucidating the genetic architecture of autism by deep genomic sequencing Gibbs, Richard Baylor College of Medicine
2/5-Elucidating the genetic architecture of autism by deep genomic sequencing Daly, Mark Broad Institue, Inc.
3/5-Elucidating the genetic architecture of autism by deep genomic sequencing Buxbaum, Joseph Mount Sinai School of Medicine
4/5-Elucidating the genetic architecture of autism by deep genomic sequencing Schellenberg, Gerard University of Pennsylvania
5/5-Elucidating the genetic architecture of autism by deep genomic sequencing Sutcliffe, James Vanderbilt University
A systems biology approach to unravel the underlying functional modules of ASD Iakoucheva, Lilia University of California, San Diego
Biological correlates of altered brain growth in autism Vaccarino, Flora Yale University
Genetic study of restricted repetitive behavior in autism spectrum disorders Kim, Soo-Jeong University of Florida
Genomic profiling and functional mutation analysis in autism spectrum disorders State, Matthew Yale University
Human autism genetics and activity-dependent gene activation Walsh, Christopher Children's Hospital Boston
Neural and phenotypic correlates of autism risk genes Bookheimer, Susan University of California, Los Angeles