Strategic Plan Objective Detail
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Question 1: Long-term Objective A  

$16,465,034.00
Fiscal Year: 2009

Green dot: Objective has greater than or equal to the recommended funding.1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Download 2009 Question 1: Long-term Objective A projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Validation study of atypical dynamic pupillary light reflex as a biomarker for autism Yao, Gang University of Missouri
The ontogeny of social visual engagement in infants at risk for autism Klin, Ami Yale University
The genetic link between autism and structural cerebellar malformations Millen, Kathleen University of Chicago
Temporal coordination of social communicative behaviors in infant siblings of children with autism Parlade, Meaghan University of Pittsburgh
Supplement to NIH ACE Network grant: "A longitudinal MRI study of infants at risk for autism" Piven, Joseph University of North Carolina at Chapel Hill
Studying the biology and behavior of autism at 1-year: The Well-Baby Check-Up Approach Pierce, Karen University of California, San Diego
Social communication phenotype of ASD in the second year Wetherby, Amy Florida State University
Signatures of gene expression in autism spectrum disorders Kunkel, Louis Children's Hospital Boston
Pupil size and circadian salivary variations in autism spectrum disorder Colombo, John University of Kansas
Prospective study of infants at high risk for autism Chawarska, Katarzyna Yale University
Predicting outcome at age 5 of younger siblings of children with ASD Malesa, Elizabeth Vanderbilt University
Placental vascular tree as biomarker of autism/ASD risk Salafia, Carolyn Research Foundation for Mental Hygiene, Inc.
Oxytocin biology and the social deficits of autism spectrum disorders Parker, Karen Stanford University
Nonlinguistic vocalizations in autism: Acoustic cry analysis in early infancy Sheinkopf, Stephen Women and Infants Hospital of Rhode Island
Neurophysiological indices of risk and outcome in autism Webb, Sara University of Washington
Multiplexed suspension arrays to investigate newborn and childhood blood samples for potential immune biomarkers of autism Vogt, Robert Centers for Disease Control and Prevention (CDC)
Model diagnostic lab for infants at risk for autism Klin, Ami Yale University
Mitochondria and autism Wallace, Douglas; Gargus, Jay; Golomb, Beatrice; Haas, Richard; Naviaux, Robert; Barshop, Bruce University of California, Irvine; University of California, San Diego
Misregulation of BDNF in autism spectrum disorders Hempstead, Barbara Weill Cornell Medical College
Metabolic biomarkers of autism: Predictive potential and genetic susceptibility James, Sandra Arkansas Children's Hospital Research Institute
Language development and outcome in children with autism (supplement) Naigles, Letitia University of Connecticut
Language development and outcome in children with autism Naigles, Letitia University of Connecticut
Infants at risk of autism: A longitudinal study (supplement) Ozonoff, Sally University of California, Davis
Infants at risk of autism: A longitudinal study Ozonoff, Sally University of California, Davis
Identifying gastrointestinal (GI) conditions in children with autism spectrum disorders (ASD) Winter, Harland Harvard Medical School