Strategic Plan Objective Detail
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Question 1: Long-term Objective A  

$13,270,044.50
Fiscal Year: 2010

Green dot: Objective has greater than or equal to the recommended funding.1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.

Download 2010 Question 1: Long-term Objective A projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Abnormal vestibulo-ocular reflexes in autism: A potential endophenotype White, Keith University of Florida
ACE Center: Assessment Core Klin, Ami Yale University
ACE Center: Clinical Phenotype: Recruitment and Assessment Core Pierce, Karen University of California, San Diego
ACE Center: Gaze perception abnormalities in infants with ASD Chawarska, Katarzyna Yale University
ACE Center: Integrated Biostatistical and Bioinformatic Analysis Core (IBBAC) Schork, Nicholas University of California, San Diego
ACE Center: Linguistic and social responses to speech in infants at risk for autism Kuhl, Patricia University of Washington
ACE Center: MRI studies of early brain development in autism Courchesne, Eric University of California, San Diego
ACE Network: A longitudinal MRI study of infants at risk for autism Piven, Joseph University of North Carolina at Chapel Hill
A longitudinal 3-D MRSI study of infants at high risk for autism Dager, Stephen University of Washington
Are autism spectrum disorders associated with leaky-gut at an early critical period in development? Dobkins, Karen; Schmid-Schoenbein, Geert University of California, San Diego
Biomarkers for autism and for gastrointestinal and sleep problems in autism Anderson, George Yale University
Brain-behavior growth charts of altered social engagement in ASD infants Klin, Ami Yale University
Defining high and low risk expression of emotion in infants at risk for autism Hannigen, Sarah University of Pittsburgh
Developmental characteristics of MRI diffusion tensor pathway changes in autism Conturo, Thomas Washington University
Development of neural pathways in infants at risk for autism spectrum disorders Dobkins, Karen University of California, San Diego
Development of neural pathways in infants at risk for autism spectrum disorders (supplement) Dobkins, Karen University of California, San Diego
Early identification of autism: A prospective study Iverson, Jana University of Pittsburgh
Early social and emotional development in toddlers at genetic risk for autism Campbell, Susan University of Pittsburgh
Electrophysiological, metabolic and behavioral markers of infants at risk Nelson, Charles Children's Hospital Boston
Family/Genetic study of autism Smith, Christopher Southwestern Autism Research & Resource Center (SARRC)
Identification of lipid biomarkers for autism Kang, Jing Massachusetts General Hospital
Identifying gastrointestinal (GI) conditions in children with autism spectrum disorders (ASD) Winter, Harland Harvard Medical School
Infants at risk of autism: A longitudinal study Ozonoff, Sally University of California, Davis
Metabolic biomarkers of autism: Predictive potential and genetic susceptibility James, Sandra Arkansas Children's Hospital Research Institute
Misregulation of BDNF in autism spectrum disorders Hempstead, Barbara Weill Cornell Medical College