Strategic Plan Objective Detail
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Question 3: Short-term Objective F  

$2,952,960.00
Fiscal Year: 2009

New! Yellow dot: Objective has some degree of funding, but less than the recommended amount.3SF. Initiate studies on at least 10 environmental factors identified in the recommendations from the 2007 IOM report "Autism and the Environment: Challenges and Opportunities for Research" as potential causes of ASD by 2012. Estimated cost $56,000,000 over 2 years.

Download 2009 Question 3: Short-term Objective F projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Assisted reproductive treatments and risk of autism Reichenberg, Avi Institute of Psychiatry, King's College London
Autism in a fish eating population Davidson, Philip University of Rochester
Effect of oxytocin receptor inhibitor (atosiban) during the perinatal period and prevalence of autism spectrum disorders Ebstein, Richard Hebrew University
Epigenetics, hormones and sex differences in autism incidence Rissman, Emile University of Virginia
Genetic and epigenetic interactions in a mouse model for autism Carpenter, Ellen David Geffen School of Medicine at University of California, Los Angeles
Immunopathogenesis in autism: Regulatory T cells and autoimmunity in neurodevelopment DeWitt, Jamie East Carolina University
Investigating gene-environment interaction in autism: Air pollution X Genetics McConnell, Rob University of Southern California
Molecular and environmental influences on autism pathophysiology Kornblum, Harley University of California, Los Angeles
Prenatal exposure to polyfluoroalkyl compounds in the EMA study Croen, Lisa Kaiser Foundation Research Institute
The CHARGE Study: Childhood Autism Risks from Genetics and the Environment (supplement) Hertz-Picciotto, Irva University of California, Davis
The CHARGE Study: Childhood Autism Risks from Genetics and the Environment (supplement) Hertz-Picciotto, Irva University of California, Davis
Toxicant-induced autism and mitochondrial modulation of nuclear gene expression Wlodarczyk, Bogdan Texas A&M University
Vaccine safety datalink thimerosol and autism study DeStefano, Frank Centers for Disease Control and Prevention (CDC)
Vitamin D status and autism spectrum disorder: Is there an association? Hammock, Bruce University of California, Davis

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Initiate studies on at least 10 environmental factors identified in the recommendations from the 2007 IOM report "Autism and the Environment: Challenges and Opportunities for Research" as potential causes of ASD by 2012.

IACC Recommended Budget: $56,000,000 over 2 years (revised in 2010)
3.1
$7,600,673
19 projects

3.S.F
$2,952,960
14 projects

3.S.F
$166,362
5 projects

3.S.F
$0
3 projects

3.S.F
$75,000
1 project

$10,794,995
3.S.F. Funding: The recommended budget was partially met.

Progress: There has been a significant decrease in the number of studies related to this objective.

Remaining Gaps, Needs, and Opportunities: Further work in this area is needed, and work should focus on identifying the directionality of associations between environmental factors and ASD (causal, reactive, or independent) in order to be applied to prevention and the development of therapeutics. Sophisticated methods that are being applied in other fields need to be brought into autism research.