|Project Title||Principal Investigator||Institution|
|Writing instruction for children with autism spectrum disorders: A study of self-regulation and strategy use||Asaro-Saddler, Kristie||University at Albany, State University of New York|
|Treatment for autism||Leon, Michael||University of California, San Diego|
|Training outpatient clinicians to deliver cognitive behavior therapy to children||Reaven, Judy||University of Colorado Denver|
|The effects of a reciprocal questioning intervention on the reading comprehension and social communication of students with autism spectrum disorder||Whalon, Kelly||The College of William and Mary|
|Safety and efficacy of complementary and alternative medicine for autism spectrum disorders||Bent, Stephen||University of California, San Francisco|
|Robotics and speech processing technology for the facilitation of social communication training in children with autism||Narayanan, Shrikanth||University of Southern California|
|Probiotics and vitamin D in ASD||Stubbs, Gene||Autism Research and Resources of Oregon (ARRO)|
|Parents and professionals attitudes to dietary interventions in ASD (PADIA)||Le Couteur, Ann||Newcastle University|
|Intranasal oxytocin for the treatment of children and adolescents with autism spectrum disorders (ASD)||Anagnostou, Evdokia||Holland Bloorview Kids Rehabilitation Hospital|
|Folate rechallenge: A pilot study||Beaudet, Arthur||Baylor College of Medicine|
|Feeding problems in children with ASD: Impact of parent education in modifying aberrant eating habits||Sharp, William||Marcus Institute|
|Evaluation of sensory integration treatment in ASD||Camarata, Stephen; Wallace, Mark||Vanderbilt University|
|Effects of therapeutic horseback riding on children and adolescents with autism spectrum disorders||Gabriels, Robin||University of Colorado Denver|
|Effectiveness of sensory based strategies for improving adaptive behaviors in children with autism||Schaaf, Roseann||Thomas Jefferson University|
|Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD||Tierney, Elaine||Kennedy Krieger Institute|
|Double-blind placebo controlled trial of subcutaneous methyl B12 on behavioral and metabolic measures in children with autism||Hendren, Robert||University of California, Davis|
|A randomized, double blind, placebo controlled study of fatty acid supplementation in autism||Carpenter, Laura||Medical University of South Carolina|
|Acupressure and acupuncture as an intervention with children with autism||Warren, Lana||Kennedy Krieger Institute|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012.
IACC Recommended Budget: $27,800,000 over 5 years
|4.S.C. Funding: The recommended budget was partially met.
Progress: Several projects were funded in this area, but more work is needed, as this is an area of significant public interest.
Remaining Gaps, Needs, and Opportunities: Experts discussed the best balance between developing new treatments and testing current treatments that lack evidence, especially when funds are limited and conclusive clinical trials are expensive. The group noted that interventions for minimally verbal children are needed; some projects on assistive communication technologies, robotics and speech processing technology to assist with social communication training are funded, but more are needed. There are other projects related to minimally verbal autism in objective 4.S.G. Small pilot studies on nutritional therapies (i.e., GFCF diet studies) have been conducted with inconclusive outcomes, demonstrating the necessity for further exploration of nutritional interventions. Future emphasis on scientific investment in sensory integration and assisted technologies is needed.