|Project Title||Principal Investigator||Institution|
|Project 1: Effect of multi-level environmental exposure on birth outcomes||Tager, Ira||University of California, Berkeley|
|UC Davis Children's Environmental Health and Disease Prevention Research Center||Pessah, Isaac||University of California, Davis|
|Center for Genomic and Phenomic Studies in Autism||Lajonchere, Clara||University of Southern California|
|Genetics and gene-environment interactions in a Korean epidemiological sample of autism||Kim, Young Shin||Yale University|
|The CHARGE Study: Childhood Autism Risks from Genetics and the Environment||Hertz-Picciotto, Irva||University of California, Davis|
|Vitamin D status and autism spectrum disorder: Is there an association?||Hammock, Bruce||University of California, Davis|
|Genome-wide environment interaction study for autism: The SEED study||Fallin, Margaret; Newschaffer, Craig||Johns Hopkins University|
|Prenatal and neonatal biologic markers for autism||Croen, Lisa||Kaiser Foundation Research Institute|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene-environment research by 2011. |
IACC Recommended Budget: $27,800,000 over 5 years
|3.S.C. Funding: The recommended budget was nearly met, but work still needs to continue on this objective. |
Progress: The funding allocated to this area so far has primarily supported building infrastructure that can now be expanded to include more subjects, more data, and more analytical projects. Studies such as the MARBLES (Markers of Autism Risk in Babies Learning Early Signs) cohort study and the CHARGE (Childhood Autism Risks from Genetics and the Environment) study are included under this objective.
Remaining Gaps, Needs, and Opportunities: Continued benefit will be derived from past investments as these resources are expanded and pooled.