|Project Title||Principal Investigator||Institution|
|The creation of ASDRA (Autism Spectrum Disorder Risk Alert)||Tiranoff, Louise||Tiranoff Productions, LLC|
|Naturalistic observation diagnostic assessment for autism||Smith, Christopher||Southwestern Autism Research & Resource Center (SARRC)|
|Think Asperger's||Smith, Christopher||Southwestern Autism Research & Resource Center (SARRC)|
|Automated measurement of dialogue structure in autism||Roark, Brian||Oregon Health & Science University|
|Autism dysmorphology measure validity study||Miles, Judith||University of Missouri|
|1/2 Development of a screening interview for research studies of ASD||Lord, Catherine||University of Michigan|
|Development of a brief screener for research in autism spectrum disorders||Lord, Catherine||University of Michigan|
|Improving accuracy and accessibility of early autism screening||Howard, Barbara||Total Child Health, Inc.|
|Early detection of pervasive developmental disorders||Fein, Deborah||University of Connecticut|
|Early detection of pervasive developmental disorders (supplement)||Fein, Deborah||University of Connecticut|
|Psychometric evaluation of the autism symptom diagnostic scale||Dixon, Dennis||Center for Autism and Related Disorders (CARD)|
|Quantitative analysis of craniofacial dysmorphology in autism||Deutsch, Curtis||University of Massachusetts Medical School|
|Computer adaptive testing of adaptive behavior of children and youth with autism||Coster, Wendy||Boston University|
|2/2 Development of a screening interview for research studies of ASD||Bishop, Somer||Cincinnati Children's Hospital Medical Center|
|Biomarkers and diagnostics for ASD||Bahn, Sabine||Institute of Biotechnology|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Develop, with existing tools, at least one efficient diagnostic instrument (i.e., briefer, less time intensive) that is valid in diverse populations for use in large-scale studies by 2011.
IACC Recommended Budget: $5,300,000 over 2 years
|1.S.A. Funding: The recommended budget was met. Significantly more than the recommended minimum budget was allocated to projects specific to this objective.
Progress: Though several projects are underway to develop efficient screeners and diagnostic tools, the overarching aim of this objective has not yet been achieved.
Remaining Gaps, Needs, and Opportunities: In addition to efficiency, emphasis should be placed on developing cost-effective, performance-based tools, and on validating these across diverse populations. Recent RFAs issued by NIMH and Autism Speaks that focus on parental engagement and early access to care could result in projects that address this objective. Currently, many screening tools exist, and these tools in many cases can be adapted for broader uses, but improved diagnostic tools remain an outstanding need.