Strategic Plan Objective Detail
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Question 3: Long-term Objective C  

$820,320.00
Fiscal Year: 2010

Yellow dot: Objective has some degree of funding, but less than the recommended amount.3LC. Determine the effect of at least five environmental factors on the risk for subtypes of ASD in the pre- and early postnatal period of development by 2015. IACC Recommended Budget: $25,100,000 over 7 years.

Download 2010 Question 3: Long-term Objective C projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Maternal risk factors for autism spectrum disorders in children of the Nurses' Health Study II Ascherio, Alberto Harvard University
Maternal risk factors for autism in the Nurses Health Study II – a pilot study Ascherio, Alberto Harvard School of Public Health
Project 1: Environmental epidemiology of autism Hertz-Picciotto, Irva University of California, Davis
Investigating the effect of mercury on ASD, AD and ASD regression Hitlan, Robert University of Northern Iowa
Novel animal models of impaired social behavior and anxiety: A role for MeCP2 Reyes, Teresa University of Pennsylvania
Maternal risk factors for autism spectrum disorders in children of the Nurses' Health Study II Santangelo, Susan Massachusetts General Hospital
Maternal dietary factors and risk of autism spectrum disorders Santangelo, Susan Harvard Medical School
IL-6-mediated Jak2/Stat3 signaling and brain development Tan, Jun University of South Florida
Immune biomarkers in serum and newborn dried blood spots Vogt, Robert Centers for Disease Control and Prevention (CDC)
Maternal risk factors for autism spectrum disorders in children of the Nurses' Health Study II Weisskopf, Marc Harvard University

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Determine the effect of at least five environmental factors on the risk for subtypes of ASD in the prenatal and early postnatal period of development by 2015.

IACC Recommended Budget: $25,100,000 over 7 years
3.6
$1,803,628
13 projects

3.L.C
$1,992,228
10 projects

3.L.C
$820,320
10 projects

3.L.C
$379,913
5 projects

3.L.C
$353,000
5 projects

$5,349,089
3.L.C. Funding: The recommended budget was partially met, and several projects were funded, but it appears there is a downward trend in funding for these projects over time. This objective partially overlaps with 3.L.A.

Progress: Epidemiological studies coded to other objectives (e.g., EARLI) may also represent progress in this area.

Remaining Gaps, Needs, and Opportunities: A barrier to the completion of this objective is the undefined nature of ASD subtypes, both phenotypically and etiologically, lack of prenatal samples, and the lack of longitudinal follow-up of at-risk subgroups. This field is still developing and needs support.