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Question 3: Short-term Objective E  

$1,739,199.65
Fiscal Year: 2009

New! Yellow dot: Objective has some degree of funding, but less than the recommended amount.3SE. Support at least two studies to determine if there are subpopulations that are more susceptible to environmental exposures (e.g., immune challenges related to infections, vaccinations, or underlying autoimmune problems) by 2012. IACC Recommended Budget: $8,000,000 over 2 years.

Download 2009 Question 3: Short-term Objective E projects (EXCEL)
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Project Title Principal Investigator Institution
Brain glutamate concentrations in autistic adolescents by MRS Anagnostou, Athanasius Mount Sinai School of Medicine
Vaccination with regression study Davis, Robert Kaiser Permanente Georgia
Psychosis and autoimmune diseases in Denmark Eaton, William Johns Hopkins University
Epidemiologic studies of reproductive and developmental outcomes – Denmark Kjaergaard, Soren Aarhus University
Interactions of environment and molecular pathways on brain overgrowth in autism: Maternal inflammation and the PI3/AKT pathway Lebelle, Janel University of California, Los Angeles
Genome-wide association study of autism characterized by developmental regression Molloy, Cynthia Cincinnati Children's Hospital Medical Center
Vulnerability phenotypes and susceptibility to environmental toxicants: From organism to mechanism Noble, Mark University of Rochester
Influence of maternal cytokines during pregnancy on effector and regulatory T helper cells as etiological factors in autism Ponzio, Nicholas University of Medicine & Dentistry of New Jersey
Influence of maternal cytokines on activation of the innate immune system as a factor in the development of autism Ponzio, Nicholas University of Medicine & Dentistry of New Jersey
Influence of the maternal immune response on the development of autism Ponzio, Nicholas University of Medicine & Dentistry of New Jersey
Evaluation of the immune and physiologic response in children with autism following immune challenge Van de Water, Judy University of California, Davis
Immunobiology in autism Van de Water, Judy University of California, Davis
Etiology of autism risk involving MET gene and the environment Van de Water, Judy University of California, Davis