|Project Title||Principal Investigator||Institution|
|Comparison of high to low intensity behavioral intervention||Granpeesheh, Doreen||Center for Autism and Related Disorders (CARD)|
|1/2-Effects of parent-implemented intervention for toddlers with autism spectrum disorder||Wetherby, Amy||Florida State University|
|1/2-Effects of parent-implemented intervention for toddlers with autism spectrum disorder (supplement)||Wetherby, Amy||Florida State University|
|Effects of parent-implemented intervention for toddlers with autism spectrum disorders||Wetherby, Amy; Lord, Catherine||Florida State University; University of Michigan|
|Parent-mediated vs. center-based intervention for toddlers with ASD: An RCT||Landa, Rebecca||Kennedy Krieger Institute|
|ACE Network: A multi-site randomized study of intensive treatment for toddlers with autism||Rogers, Sally||University of California, Davis|
|Autism Intervention Research Network on Behavioral Health (AIR-B network)||Kasari, Connie||University of California, Los Angeles|
|2/2-Effects of parent-implemented intervention for toddlers with autism spectrum disorder||Lord, Catherine||University of Michigan|
|2/2-Effects of parent-implemented intervention for toddlers with autism spectrum disorder (supplement)||Lord, Catherine||University of Michigan|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Complete two multi-site randomized controlled trials of comprehensive early intervention that address core symptoms, family functioning and community involvement by 2013.
IACC Recommended Budget: $16,700,000 over 5 years
|4.S.D. Funding: The recommended budget was met. Significantly more than the recommended minimum budget was allocated to projects specific to this objective.
Progress: In 2011 and 2012, ~20 trials were supported, including a mix of trial sizes.Â
Remaining Gaps, Needs, and Opportunities: There is a need for both small, pilot studies and larger, robustly powered studies in this area. Several larger studies in the past few years (e.g., Early Start Denver Model) have emerged, but most studies in this area are generally smaller than in other fields of medicine and therefore lack the power to be informative if negative or definitive if positive. This objective also cites "family functioning" and "community living," which may have significant overlap with objectives in Questions 5 and 6 of the Strategic Plan.