|Project Title||Principal Investigator||Institution|
|Multiple social tasks and social adjustment||Kang, Sun-Mee||California State University, Northridge|
|Collaborative research: Computational behavioral science: Modeling, analysis, and visualization of social and communicative behavior||Dey, Anind||Carnegie Mellon University|
|Electrophysiological signatures of language impairment in autism spectrum disorder||Roberts, Timothy||Children's Hospital of Philadelphia|
|Electrophysiological signatures of language impairment in autism spectrum disorder (supplement)||Roberts, Timothy||Children's Hospital of Philadelphia|
|Video game environments for the integrative study of perception, attention and social cognition in autism and autism sibs||Belmonte, Matthew||Cornell University|
|Collaborative research: Computational behavioral science: Modeling, analysis, and visualization of social and communicative behavior||Rehg, James||Georgia Tech Research Corporation|
|Autism spectrum disorder in Down syndrome: A model of repetitive and stereotypic behavior for idiopathic ASD||Kaufmann, Walter||Kennedy Krieger Institute|
|Autism: Social and communication predictors in siblings||Landa, Rebecca||Kennedy Krieger Institute|
|Imitation in autism||Bolton, Patrick||King's College London|
|A prospective multi-system evaluation of infants at risk for autism||Bauman, Margaret||Massachusetts General Hospital|
|A prospective multi-system evaluation of infants at risk for autism||Herbert, Martha||Massachusetts General Hospital|
|Collaborative research: Computational behavioral science: Modeling, analysis, and visualization of social and communicative behavior||Picard, Rosalind||Massachusetts Institute of Technology|
|Growth and maturation in children with autism||Louis, Germaine||National Institutes of Health|
|Clinical and behavioral phenotyping of autism and related disorders||Swedo, Susan||National Institutes of Health|
|Using a direct observation assessment battery to assess outcome of early intensive behavioral intervention for children with autism||MacDonald, Rebecca||New England Center for Children|
|Translational developmental neuroscience of autism||Di Martino, Adriana||New York University School of Medicine|
|Functional brain networks in autism and attention deficit hyperactivity disorder||Nigg, Joel||Oregon Health & Science University|
|HCC: Medium: Automatic detection of atypical patterns in cross-modal affect||Van Santen, Jan||Oregon Health & Science University|
|A novel quantitative framework to study lack of social interactions in autism||Torres, Elizabeth||Rutgers, The State University of New Jersey - New Brunswick|
|Sclaroff, Stan||Trustees of Boston University|
|Electrophysiological correlates of cognitive control in autism||Takarae, Yukari||University of California, Davis|
|Cellular structure of the amygdala in autism||Morgan, John||University of California, Davis|
|Analyses of brain structure and connectivity in young children with autism||Nordahl, Christine||University of California, Davis|
|Validity of an anxious subtype in autism spectrum disorders||Sterling, Lindsey||University of California, Los Angeles|
|Neuroimaging of autism spectrum disorders||Schultz, Robert||University of California, Los Angeles|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015.
IACC Recommended Budget: $71,100,000 over 5 years
|1.L.B. Funding: The recommended budget was partially met.
Progress: Over 50 projects were supported in this area. While behavioral and/or biological heterogeneity are well covered by existing projects, gaps still exist in relating these measures to etiology and risk, treatment response, and/or outcomes.
Remaining Gaps, Needs, and Opportunities: There was a discussion of whether this objective should be expanded to be compatible with the Research Domain Criteria (RDoC) now being used by NIMH, which focus on functional domains rather than disorder-specific characteristics.