|Project Title||Principal Investigator||Institution|
|Measuring quality adjusted life years in children with autism spectrum disorders||Tilford, John||Arkansas Children's Hospital Research Institute|
|Characterizing ASD phenotypes by multimedia signal and natural language processing||Elhadad, Noemie||Columbia University|
|Language learning in autism||Ullman, Michael||Georgetown University|
|Prosodic and pragmatic processes in highly verbal children with autism||Snedeker, Jesse||President & Fellows of Harvard College|
|Neocortical mechanisms of categorical speech perception||Chang, Edward||University of California, San Francisco|
|Asperger's syndrome: Diagnosis, interpretation and impact||Nickrenz, Elizabeth||University of Chicago|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Identify and develop measures to assess at least three "continuous dimensions" (i.e., social reciprocity, communication disorders, and repetitive/restrictive behaviors) of ASD symptoms and severity that can be used by practitioners and/or families to assess response to intervention for people with ASD across the lifespan by 2016.
IACC Recommended Budget: $18,500,000 over 5 years
|1.L.C. Funding: The recommended budget was partially met.
Progress: Basic science and clinical aspects of the research are underway, but more work is needed for the studies to be applied for use by practitioners and/or families.
Remaining Gaps, Needs, and Opportunities: There is a need for finer ways to quantify social behavior and detect change in response to successful treatment. There is a need to move toward performance-based measures and away from the checklist approach.