|Project Title||Principal Investigator||Institution|
|Longitudinal neurogenetics of atypical social brain development in autism||Pelphrey, Kevin||Yale University|
|Analysis of brain microstructure in autism using novel diffusion MRI approaches||Conturo, Thomas||Washington University School of Medicine|
|Communication and prosody in autism: A pilot fMRI study using a sib-pair design||Gusnard, Debra||Washington University in St. Louis|
|Impacts of parenting adolescents & adults with autism||Seltzer, Marsha||University of Wisconsin - Madison|
|Electrical measures of functional cortical connectivity in autism||Murias, Michael||University of Washington|
|Investigation of the link between early brain enlargement and abnormal functional connectivity in autism spectrum disorders||Kleinhans, Natalia||University of Washington|
|Quantifying white matter connectivity in autism||Lainhart, Janet||University of Utah|
|Visual perspective-taking and the acquisition of American Sign Language by deaf children with autism||Shield, Aaron||University of Texas at Austin|
|Neural basis of audiovisual integration during language comprehension in autism||Bennetto, Loisa||University of Rochester|
|A longitudinal MRI study of infants at risk for autism- Supplemental||Piven, Joseph||University of North Carolina at Chapel Hill|
|Multisensory processing in autism||Essick, Gregory||University of North Carolina at Chapel Hill|
|MRI study of brain development in school age children with autism||Hazlett, Heather Cody||University of North Carolina at Chapel Hill|
|A longitudinal MRI study of infants at risk for autism||Piven, Joseph||University of North Carolina at Chapel Hill|
|The neural correlates of transient and sustained executive control in children with autism spectrum disorder||Christ, Shawn||University of Missouri|
|Neural correlates of serotonin transporter gene polymorphisms and social impairment in ASD||Monk, Christopher||University of Michigan|
|FMRI evidence of genetic influence on rigidity in ASD||Lee, Jillian||University of Michigan|
|Exploring functional brain connectivity for visual cognition in autism spectrum disorder||Joseph, Jane||University of Kentucky|
|FMRI studies of cerebellar functioning in autism||Mosconi, Matthew||University of Illinois at Chicago|
|Mimicry and imitation in ASDs||Fein, Deborah||University of Connecticut|
|Gamma band dysfunction as a local neuronal connectivity endophenotype in autism||Rojas, Donald||University of Colorado Denver|
|Stereological analyses of neuron numbers in frontal cortex from age 3 years to adulthood in autism||Courchesne, Eric||University of California, San Diego|
|Collaborative neuropathology workgroup: A comprehensive multilevel analysis of frontal lobe microstructure in autism||Courchesne, Eric||University of California, San Diego|
|Neural basis of socially driven attention in children with autism||Greene, Deanna||University of California, Los Angeles|
|Behavioral and functional neuroimaging investigations of visual perception and cognition in autistics||Mottron, Laurent||Université de Montréal|
|Dendritic organization within the cerebral cortex in autism||Gabbott, Paul||The Open University|
|IACC Strategic Plan Objectives||2008||2009||2010||2011||2012||Total|
|Complete a large-scale, multidisciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020.
IACC Recommended Budget: $126,200,000 over 12 years
|2.L.A. Funding: The recommended budget was partially met.
Progress: Several projects have been funded in this area, and the ACE Network continues to collect data relevant to this objective.
Remaining Gaps, Needs and Opportunities: Though this research is underway, more clinical studies are needed over a longer trajectory to identify issues faced as people with ASD age, especially with regard to risk factors for other medical conditions. Another remaining need is that of standardization of data collection and analysis methods.