|Project Title||Principal Investigator||Institution|
|Interdisciplinary investigation of biological signatures of autism subtypes||Amaral, David; Rogers, Sally; Van de Water, Judy||University of California, Davis|
|MRI study of brain development in school age children with autism||Hazlett, Heather Cody||University of North Carolina at Chapel Hill|
|Pragmatic skills of young males and females with fragile X syndrome||Martin, Gary||University of North Carolina at Chapel Hill|
|Pragmatic skills of young males and females with fragile X syndrome (supplement)||Martin, Gary||University of North Carolina at Chapel Hill|
|20-year outcome of autism||McMahon, William||University of Utah|
|Investigation of the link between early brain enlargement and abnormal functional connectivity in autism spectrum disorders||Kleinhans, Natalia||University of Washington|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Complete a large-scale, multidisciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020. |
IACC Recommended Budget: $126,200,000 over 12 years
|2.L.A. Funding: The recommended budget was partially met. |
Progress: Several projects have been funded in this area, and the ACE Network continues to collect data relevant to this objective.
Remaining Gaps, Needs and Opportunities: Though this research is underway, more clinical studies are needed over a longer trajectory to identify issues faced as people with ASD age, especially with regard to risk factors for other medical conditions. Another remaining need is that of standardization of data collection and analysis methods.