Strategic Plan Objective Detail
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Question 3: Objective 1  

$7,600,673.00
Fiscal Year: 2008

Yellow dot: Objective has some degree of funding, but less than the recommended amount.3.1 Initiate studies on at least five environmental factors identified in the recommendations from the 2007 IOM report “Autism and the Environment: Challenges and Opportunities for Research” as potential causes of ASD by 2010. IACC Recommended Budget: $23,600,000 over 2 years.

Download 2008 Question 3: Objective 1 projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Investigation of measles virus sequences in bowel biopsies of children with ASD * No PI listed Centers for Disease Control and Prevention
Vaccine Safety Datalink thimerosol and autism study * No PI listed Centers for Disease Control and Prevention
Centers for autism and developmental disabilities research and epidemiology - 4 Miller, Lisa Colorado Department of Health and Environment
Danish Agency for Science, Technology and Innovation Christiansen, Anne Danish Agency for Science, Technology and Innovation
Centers for autism and developmental disabilities research and epidemiology - 3 Fallin, Dani Johns Hopkins University
Centers for autism and developmental disabilities research and epidemiology - 1 Croen, Lisa Kaiser Foundation Research Institute
Centers for autism and developmental disabilities research and epidemiology - data coordinating center Reed, Phillip Michigan State University
Centers for autism and developmental disabilities research and epidemiology - 6 Schendel, Diana; Schieve, Laura National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention
Differential effects of thimerosal on cell division and apoptosis in normal vs. autism spectrum disorder cell lines Baskin, David The Methodist Hospital Houston
Italy thimerosol neurodevelopmental disabilities study * No PI listed Unavailable
Analysis of developmental interactions between reelin haploinsufficiency, male sex, and mercury exposure Keller, Flavio Universita Campus Bio-Medico di Roma
Vitamin D status and autism spectrum disorder: Is there an association? Hammock, Bruce University of California, Davis
A non-human primate autism model based on maternal immune activation Patterson, Paul University of California, Davis
Molecular and environmental influences on autism pathophysiology Kornblum, Harley University of California, Los Angeles
Centers for autism and developmental disabilities research and epidemiology - 2 Daniels, Julie University of North Carolina at Chapel Hill
Centers for autism and developmental disabilities research and epidemiology - 5 Pinto-Martin, Jennifer University of Pennsylvania/Children's Hospital of Philadelphia
Autism in a fish eating population Davidson, Philip University of Rochester
Measuring Hg body burden in 3 groups Kern, Janet University of Texas
Epigenetics, hormones and sex differences in autism incidence Rissman, Emile University of Virginia

Objective Cumulative Funding Table

IACC Strategic Plan Objectives 2008 2009 2010 2011 2012 Total
Initiate studies on at least 10 environmental factors identified in the recommendations from the 2007 IOM report "Autism and the Environment: Challenges and Opportunities for Research" as potential causes of ASD by 2012.

IACC Recommended Budget: $56,000,000 over 2 years (revised in 2010)
3.1
$7,600,673
19 projects

3.S.F
$2,952,960
14 projects

3.S.F
$166,362
5 projects

3.S.F
$0
3 projects

3.S.F
$75,000
1 project

$10,794,995
3.S.F. Funding: The recommended budget was partially met.

Progress: There has been a significant decrease in the number of studies related to this objective.

Remaining Gaps, Needs, and Opportunities: Further work in this area is needed, and work should focus on identifying the directionality of associations between environmental factors and ASD (causal, reactive, or independent) in order to be applied to prevention and the development of therapeutics. Sophisticated methods that are being applied in other fields need to be brought into autism research.