Strategic Plan Objective Detail
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Question 4: Short-term Objective C  

$3,252,940.71
Fiscal Year: 2009

Yellow dot: Objective has some degree of funding, but less than the recommended amount.4SC. Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012. IACC Recommended Budget: $27,800,000 over 5 years.

Download 2009 Question 4: Short-term Objective C projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
National randomized double-blind, placebo-controlled vitamin/mineral study Adams, Jim Arizona State University
Intranasal oxytocin for the treatment of children and adolescents with autism spectrum disorders (ASD) Anagnostou, Evdokia Holland Bloorview Kids Rehabilitation Hospital
Writing instruction for children with autism spectrum disorders: A study of self-regulation and strategy use Asaro-Saddler, Kristie University at Albany, State University of New York
Folate rechallenge: A pilot study Beaudet, Arthur Baylor College of Medicine
Safety and efficacy of complementary and alternative medicine for autism spectrum disorders Bent, Stephen University of California, San Francisco
Peer-mediated interventions for elementary school students with autism spectrum disorders Blakeley-Smith, Audrey University of Colorado Denver
Peer-mediated interventions for elementary school students with autism spectrum disorders Blakeley-Smith, Audrey University of Colorado Denver
Communication success and AAC: A model of symbol acquisition Brady, Nancy University of Kansas
Communication success and AAC: A model of symbol acquisition (supplement) Brady, Nancy University of Kansas
Evaluation of sensory integration treatment in ASD Camarata, Stephen Vanderbilt University
A randomized, double blind, placebo controlled study of fatty acid supplementation in autism Carpenter, Laura Medical University of South Carolina
A double-blind, randomized clinical trial of levocarnitine to treat autism spectrum disorders Geier, Mark Institute of Chronic Illnesses, Inc.
Double-blind placebo-controlled evaluation of fluconazole Granpeesheh, Doreen Center for Autism and Related Disorders (CARD)
Double-blind placebo controlled trial of subcutaneous methyl B12 on behavioral and metabolic measures in children with autism Hendren, Robert University of California, Davis
Parents and professionals attitudes to dietary interventions in ASD (PADIA) Le Couteur, Ann Newcastle University
Double-blind, placebo-controlled crossover study of glutathione, vitamin C and cysteine in children with autism and behavior problems Mcclamroch, Margie Children's Hospital Foundation, Norton Healthcare Foundation
Robotics and speech processing technology for the facilitation of social communication training in children with autism Narayanan, Shrikanth University of Southern California
Measuring the effects of training parents to provide intervention via the Arizona Telemedicine Program Openden, Daniel Southwestern Autism Research & Resource Center (SARRC)
Training outpatient clinicians to deliver cognitive behavior therapy to children Reaven, Judy University of Colorado Denver
Effectiveness of sensory based strategies for improving adaptive behaviors in children with autism Schaaf, Roseann Thomas Jefferson University
Feeding problems in children with ASD: Impact of parent education in modifying aberrant eating habits Sharp, William Marcus Institute
Probiotics and vitamin D in ASD Stubbs, Gene Autism Research and Resources of Oregon (ARRO)
Treatment of autism spectrum disorders with a glutamate antagonist Swedo, Susan National Institutes of Health (NIH)
Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD Tierney, Elaine Kennedy Krieger Institute
Acupressure and acupuncture as an intervention with children with autism Warren, Lana Kennedy Krieger Institute

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012.

IACC Recommended Budget: $27,800,000 over 5 years
4.6
$641,285
8 projects

4.S.C
$3,252,941
29 projects

4.S.C
$1,509,745
18 projects

4.S.C
$2,254,724
18 projects

4.S.C
$1,288,226
17 projects

$8,946,921
4.S.C. Funding: The recommended budget was partially met.

Progress: Several projects were funded in this area, but more work is needed, as this is an area of significant public interest.

Remaining Gaps, Needs, and Opportunities: Experts discussed the best balance between developing new treatments and testing current treatments that lack evidence, especially when funds are limited and conclusive clinical trials are expensive. The group noted that interventions for minimally verbal children are needed; some projects on assistive communication technologies, robotics and speech processing technology to assist with social communication training are funded, but more are needed. There are other projects related to minimally verbal autism in objective 4.S.G. Small pilot studies on nutritional therapies (i.e., GFCF diet studies) have been conducted with inconclusive outcomes, demonstrating the necessity for further exploration of nutritional interventions. Future emphasis on scientific investment in sensory integration and assisted technologies is needed.