|Project Title||Principal Investigator||Institution|
|Folate rechallenge: A pilot study||Beaudet, Arthur||Baylor College of Medicine|
|Writing instruction for children with autism spectrum disorders: A study of self-regulation and strategy use||Asaro-Saddler, Kristie||University at Albany, State University of New York|
|Intranasal oxytocin for the treatment of children and adolescents with autism spectrum disorders (ASD)||Anagnostou, Evdokia||Holland Bloorview Kids Rehabilitation Hospital|
|National randomized double-blind, placebo-controlled vitamin/mineral study||Adams, Jim||Arizona State University|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
|Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012.
IACC Recommended Budget: $27,800,000 over 5 years
|4.S.C. Funding: The recommended budget was partially met.
Progress: Several projects were funded in this area, but more work is needed, as this is an area of significant public interest.
Remaining Gaps, Needs, and Opportunities: Experts discussed the best balance between developing new treatments and testing current treatments that lack evidence, especially when funds are limited and conclusive clinical trials are expensive. The group noted that interventions for minimally verbal children are needed; some projects on assistive communication technologies, robotics and speech processing technology to assist with social communication training are funded, but more are needed. There are other projects related to minimally verbal autism in objective 4.S.G. Small pilot studies on nutritional therapies (i.e., GFCF diet studies) have been conducted with inconclusive outcomes, demonstrating the necessity for further exploration of nutritional interventions. Future emphasis on scientific investment in sensory integration and assisted technologies is needed.