Strategic Plan Objective Detail
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Question 4: Short-term Objective F  

$9,791,269.68
Fiscal Year: 2009

New! Yellow dot: Objective has some degree of funding, but less than the recommended amount.4SF. Launch five randomized controlled trials of interventions including biological signatures and other measures to predict response, and monitor quality of life and functional outcomes, in each of the following groups:

Download 2009 Question 4: Short-term Objective F projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
A multi-site clinical randomized trial of the Hanen More Than Words Intervention Carter, Alice University of Massachusetts Boston
3/3 CBT for anxiety disorders in autism: Adapting treatment for adolescents Ehrenreich, Jill University of Miami
Early intervention for children screened positive for autism by the First Year Inventory Baranek, Grace; Watson, Linda; Reznick, Steven; Crais, Elisabeth University of North Carolina at Chapel Hill
Social cognition and interaction training for adolescents with high functioning autism Penn, David; Dichter, Gabriel University of North Carolina at Chapel Hill
Efficacy and sustainability of the STAR program Mandell, David University of Pennsylvania
1/3-Atomoxetine placebo and parent training in autism Handen, Benjamin University of Pittsburgh
3/3-Atomoxetine placebo and parent training in autism Smith, Tristram University of Rochester
2/3-Multisite RCT of early intervention for spoken communication in autism Smith, Tristram University of Rochester
2/3 CBT for anxiety disorders in autism: Adapting treatment for adolescents Storch, Eric University of South Florida
The mirror neuron system in children with autism Bernier, Raphael University of Washington
Intervention for infants at risk for autism Estes, Annette University of Washington
ACE Center: Risk and protective factors in the development of associated symptoms in autism Estes, Annette University of Washington
High school inclusion program for students with autism spectrum disorders Hughes, Carolyn Vanderbilt University
The intersection of autism and ADHD Reiersen, Angela Washington University in St. Louis
ACE Network: Early pharmacotherapy guided by biomarkers in autism Chugani, Diane Wayne State University
A randomized controlled trial of two treatments for verbal communication Volkmar, Fred; Paul, Rhea Yale Child Study Center
Enhancing understanding and use of conversational rules in school-aged speakers with autism spectrum disorders Austin, Sarita Yale University

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Launch randomized controlled trials of interventions including biological signatures and other measures to predict response, and monitor quality of life and functional outcomes in each of the following groups:
  • Five trials in infants and toddlers by 2013.

    IACC Recommended Budget: $30,000,000 over 5 years (revised in 2010)
  • Three trials in school-aged children and/or adolescents by 2013.

    IACC Recommended Budget: $18,000,000 over 5 years (revised in 2010)
  • Three trials in adults by 2014.

    IACC Recommended Budget: $18,000,000 over 5 years

Total IACC Recommended Budget: $66,000,000 over 5 years

4.3 & 4.4
$12,109,516
16 projects & 30 projects

4.S.F
$9,791,270
42 projects

4.S.F
$7,575,212
30 projects

4.S.F
$5,445,599
23 projects


4.S.F
$6,255,438
21 projects


$41,177,035
4.S.F. Funding: The recommended budget was partially met.

Progress: The investment in projects under this objective is making good progress toward the recommended amount, with more than 20 projects funded in 2011 and 2012.

Remaining Gaps, Needs, and Opportunities: Current projects in this area are restricted to small pilot studies, which are essential to establishing a foundation prior to expansion to larger scale work. Thus, increased investment in this area is important. It should be noted that most RCTs in the future will incorporate some aspect of biological signatures (thus potentially presenting a challenge to future coding of projects).