|Project Title||Principal Investigator||Institution|
|2/3 CBT for anxiety disorders in autism: Adapting treatment for adolescents||Storch, Eric||University of South Florida|
|ACE Center: Risk and protective factors in the development of associated symptoms in autism||Estes, Annette||University of Washington|
|The mirror neuron system in children with autism||Bernier, Raphael||University of Washington|
|ACE Network: Early pharmacotherapy guided by biomarkers in autism||Chugani, Diane||Wayne State University|
|Enhancing understanding and use of conversational rules in school-aged speakers with autism spectrum disorders||Austin, Sarita||Yale University|
|IACC Strategic Plan Objective||2008||2009||2010||2011||2012||Total|
Launch randomized controlled trials of interventions including biological signatures and other measures to predict response, and monitor quality of life and functional outcomes in each of the following groups:
Total IACC Recommended Budget: $66,000,000 over 5 years
|4.3 & 4.4
16 projects & 30 projects
|4.S.F. Funding: The recommended budget was partially met.
Progress: The investment in projects under this objective is making good progress toward the recommended amount, with more than 20 projects funded in 2011 and 2012.
Remaining Gaps, Needs, and Opportunities: Current projects in this area are restricted to small pilot studies, which are essential to establishing a foundation prior to expansion to larger scale work. Thus, increased investment in this area is important. It should be noted that most RCTs in the future will incorporate some aspect of biological signatures (thus potentially presenting a challenge to future coding of projects).