Strategic Plan Objective Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Question 1: Long-term Objective B  

$8,760,010.00
Fiscal Year: 2009

Yellow dot: Objective has some degree of funding, but less than the recommended amount.1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.

Download 2009 Question 1: Long-term Objective B projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Plasticity in autism spectrum disorders: Magnetic stimulation studies Oberman, Lindsay Beth Israel Deaconess Medical Center
Electrophysiological signatures of language impairment in autism spectrum disorder Roberts, Timothy Children's Hospital of Philadelphia
Electrophysiological signatures of language impairment in autism spectrum disorder (supplement) Roberts, Timothy Children's Hospital of Philadelphia
Reward systems in children with autism Scott, Ashley University of California, Los Angeles
Clinical and behavioral phenotyping of autism and related disorders Swedo, Susan National Institutes of Health (NIH)
Temperament, emotional expression, and emotional self-regulation in relation to later ASD diagnosis Wozniak, Robert Bryn Mawr College
Social evaluation in infants and toddlers Wynn, Karen Yale University
Predicting useful speech in children with autism (supplement) Yoder, Paul Vanderbilt University
Predicting useful speech in children with autism Yoder, Paul Vanderbilt University

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015.

IACC Recommended Budget: $71,100,000 over 5 years
1.4
$5,773,203
18 projects

1.L.B
$8,760,010
34 projects

1.L.B
$15,228,060
52 projects

1.L.B
$9,376,400
42 projects

1.L.B
$12,813,396
39 projects

$51,951,069
1.L.B. Funding: The recommended budget was partially met.

Progress: Over 50 projects were supported in this area. While behavioral and/or biological heterogeneity are well covered by existing projects, gaps still exist in relating these measures to etiology and risk, treatment response, and/or outcomes.

Remaining Gaps, Needs, and Opportunities: There was a discussion of whether this objective should be expanded to be compatible with the Research Domain Criteria (RDoC) now being used by NIMH, which focus on functional domains rather than disorder-specific characteristics.