Strategic Plan Objective Detail
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Question 4: Short-term Objective B  

$23,229,501.04
Fiscal Year: 2010

Green dot: Objective has greater than or equal to the recommended funding.4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.

Download 2010 Question 4: Short-term Objective B projects (EXCEL)
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Institution
Neural and cognitive mechanisms of autism Sur, Mriganka Massachusetts Institute of Technology
Characterization of the transcriptome in an emerging model for social behavior Thomas, James Emory University
Integrated approach to the neurobiology of autism spectrum disorders Vaccarino, Flora Yale University
Cellular and genetic correlates of increased head size in autism spectrum disorder Vaccarino, Flora Yale University
Murine genetic models of autism Veenstra-Vanderweele, Jeremy Vanderbilt University
Mouse genetic model of a dysregulated serotonin transporter variant associated with autism Veenstra-Vanderweele, Jeremy Vanderbilt University
Cntnap2 in a behavioral model of autism White, Stephanie University of California, Los Angeles
Dynamic regulation of Shank3 and ASD Worley, Paul Johns Hopkins University
Basal ganglia circuitry and molecules in pathogenesis of motor stereotypy Yang, Xiangdong University of California, Los Angeles
Vasopressin receptors and social attachment Young, Larry Emory University
Neural mechanisms of social cognition and bonding Young, Larry Emory University
Central vasopressin receptors and affiliation Young, Larry Emory University
Central vasopressin receptors and affiliation Young, Larry Emory University
Neural mechanisms of social cognition and bonding Young, Larry Emory University
Genomic resources for identifying genes regulating social behavior Young, Larry Emory University
Regulation of gene expression in the brain Young, Walter National Institutes of Health
Analysis of cortical circuits related to ASD gene candidates Zador, Anthony Cold Spring Harbor Laboratory