Strategic Plan Objective Detail
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Question 2: Short-term Objective F  

$401,595.00
Fiscal Year: 2010

Yellow dot: Objective has some degree of funding, but less than the recommended amount.2SF. Launch two studies that focus on prospective characterization of children with reported regression to investigate potential risk factors by 2012. IACC Recommended Budget: $4,500,000 over 5 years.

Download 2010 Question 2: Short-term Objective F projects (EXCEL)
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Project Title Principal Investigator Institution
Vaccination with regression study Davis, Robert Kaiser Permanente Georgia
Neuroimmunologic investigations of autism spectrum disorders (ASD) Swedo, Susan National Institutes of Health

Objective Cumulative Funding Table

IACC Strategic Plan Objective 2008 2009 2010 2011 2012 Total
Launch two studies that focus on prospective characterization of children with reported regression to investigate potential risk factors by 2012.

IACC Recommended Budget: $4,500,000 over 5 years
N/A

2.S.F
$0
0 projects

2.S.F
$401,595
2 projects

2.S.F
$339,709
3 projects

2.S.F
$251,830
2 projects

$993,134
2.S.F. Funding: The recommended budget was partially met.

Progress: The number of recommended projects has been met and progress is being made, but further work is needed to understand how autism develops. Some recent data suggest that regression may be more of a continuum than a distinct type of autism, and several studies have provided new descriptions of ASD developmental trajectories. However, other studies have found some differences between children with reported regression vs. children without reported regression.

Remaining Gaps, Needs and Opportunities: Further work is needed to better understand subtypes and potential biomarkers. High-risk siblings may present an opportunity for studying regression prospectively.