Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Multi-registry analyses for iCARE - Data Management Core  

This proposal builds on the Autism Speaks-Centers for Disease Control and Prevention (CDC) International Autism Epidemiology Network Registry Workgroup. The Workgroup established the International Collaboration for Autism Registry Epidemiology (iCARE) and identified relevant registry systems for the proposed investigation in Scandinavia (Denmark, Sweden, Finland and Norway), Australia and Israel. The goals of the investigation are 1) to establish the necessary infrastructure for multi-registry autism research, including establishing a multi-registry virtual data set approach to analysis and establishing written guidelines for multi-national registry-based research collaboration, and 2) demonstrate the capabilities of the multi-registry approach to elucidate etiological pathways to autism by thoroughly investigating candidate factors for perinatal adversity in relation to autism, beginning with gestational length and fetal growth. The study will consider variation in diagnostic criteria and trends over time, and based on heretofore unrivaled sample sizes that will permit examination of risk across more finely defined birth weight and gestational age categories; consider effects on risk of fetal size at a given gestational age; control for confounding; and conduct robust stratified analyses considering other important risk factors, such as gender, parental age, and birth multiplicity, and features of autism, such as diagnostic subtype. The proposed project presets a new scope in epidemiological investigation into risk factors for autism, and will provide the foundation and guidelines for future investigations. Project Status
ONGOING

2009

Funder Autism Speaks
Fiscal Year Funding $50,360.20
Project Number 6248
Principal Investigator Bresnahan, Michaeline
Received ARRA Funding? No
Strategic Plan Question Question 7: What Other Infrastructure and Surveillance Needs Must Be Met? (Infrastructure)
Strategic Plan Objective New! Yellow dot: Objective has some degree of funding, but less than the recommended amount. 7J. Develop the personnel and technical infrastructure to assist states, territories, and other countries who request assistance describing and investigating potential changes in the prevalence of ASD and other developmental disabilities by 2013. IACC Recommended Budget: $1,650,000 over 3 years.
Federal or Private? Private
Institution Columbia University
State/Country New York
Web Link 1 Multi-registry analyses for iCARE - Data Management Core (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Multi-registry analyses for iCARE - Data Management Core | $76,219.00 | 2010 | 6248