Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neurobiology of sociability in a mouse model system relevant to autism  

Developmental variations in social behaviors and brain growth have been relatively understudied in mouse models, but such studies are needed, given the importance of developmental variations in autism. This study will use the BALB/c and C57BL/6J mouse strains to carry out developmental studies of social behaviors, including detailed analyses of social behaviors that are relevant to autism. Possible links among social behavior and brain development endophenotypes relevant to autism will also be evaluated. Project Status
ONGOING

2009

Funder National Institutes of Health
Fiscal Year Funding $354,375.00
Project Number 5R01MH080718-03
Principal Investigator Brodkin, Edward
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution University of Pennsylvania
State/Country Pennsylvania
Web Link 1 Neurobiology of sociability in a mouse model system relevant to autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Neurobiology of sociability in a mouse model system relevant to autism | $354,375.00 | 2010 | 5R01MH080718-04
Neurobiology of sociability in a mouse model system relevant to autism | $354,375.00 | 2008 | R01MH080718-02
Neurobiology of sociability in a mouse model system relevant to autism (supplement) | $175,927.00 | 2009 | 3R01MH080718-03S1