Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Cortical mechanisms underlying visual motion processing impairments in autism  

This project will study brain processing of global and local motion signals in autism. Global motion processing requires spatiotemporal integration over a network of neural components whereas local motion processing does not. Using a psychophysical approach, Dr. Chen and colleagues will examine global and local motion perception in autism patients (n=30) and in age- and sex-matched normal controls (n=30). The investigators will measure perceptual thresholds in the detection of the directions of global and local motion. Using a functional magnetic resonance imaging (fMRI) approach, they will examine the pattern of cortical activations while autism patients (n=10) and controls (n=10) perform the global and the local motion tasks. The level of fMRI blood-oxygen-level dependence (BOLD) signal changes in both sensory (extrastriate) and cognitive (prefrontal) cortices will be measured. This study will generate empirical data on whether and how global motion perception, a sensory process that provides critical visual signals for cognitive and social functioning, is altered in autism. Project Status
ONGOING

2009

Funder Autism Speaks
Fiscal Year Funding $60,000.00
Project Number 1978
Principal Investigator Chen, Yue
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Private
Institution Harvard Medical School/McLean Hospital
State/Country Massachusetts
Web Link 1 Cortical mechanisms underlying visual motion processing impairments in autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Cortical mechanisms underlying visual motion processing impairments in autism | $0.00 | 2010 | 1978
Cortical mechanisms underlying visual motion processing impairments in autism | $60,000.00 | 2008 | 1978