Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Development of neural pathways in infants at risk for autism spectrum disorders  

Because autism spectrum disorders (ASD) is not diagnosed reliably before the second or third year of life, the best way to investigate development of the disorder involves studying infant siblings of children with ASD (High-Risk infants), who have a significantly increased risk (10- to 20-fold) of developing ASD. This study uses a neurodevelopmental approach and a variety of techniques to identify abnormalities associated with High-Risk ASD infants (ages 6 to 36 months) by tracking their development in comparison to normal infants. Abnormalities in visual processing, motion processing, face processing, and social/emotional processing will be assessed. Standardized tests will also be used to evaluate social, communicative, and cognitive skills. The hope is that these studies will shed light on the neurodevelopmental origins of ASD (and the broader autism phenotype) and aid in early diagnosis of the disorder. Project Status
ONGOING

2009

Funder National Institutes of Health
Fiscal Year Funding $328,313.00
Project Number 5R01HD052804-02
Principal Investigator Dobkins, Karen
Received ARRA Funding? No
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD by 2014. IACC Recommended Budget: $33,300,000 over 5 years.
Federal or Private? Federal
Institution University of California, San Diego
State/Country California
Web Link 1 Development of neural pathways in infants at risk for autism spectrum disorders (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Development of neural pathways in infants at risk for autism spectrum disorders | $325,029.00 | 2010 | 5R01HD052804-03
Development of neural pathways in infants at risk for autism spectrum disorders | $328,313.00 | 2008 | R01HD052804-01A2
Development of neural pathways in infants at risk for autism spectrum disorders (supplement) | $244,282.00 | 2010 | 3R01HD052804-03S1