Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

The ontogeny of social visual engagement in infants at risk for autism  

In this project, social visual engagement in infants from 2 to 24 months of age will be assessed using eye-tracking technology and innovative quantification of visual attention to study how infants with autism interact with the social world. Experimental data will be collected at 2, 4, 6, 9, 12, 18, and 24 months. A cohort of 235 infants will be enrolled in this project, consisting of 135 infant siblings of children with autism who are at High Risk for developing an ASD (HR-ASD); 50 infants at High Risk for Developmental Delays without familial history of ASD (HR-DD); and 50 children at Low Risk of developmental problems with Typical Development expected (LR-TD expected). By utilizing a longitudinal, prospective study design in at-risk infants, researchers will be able to track the developmental course of altered social engagement in infants subsequently diagnosed with an autism spectrum disorder. The three long-term goals of this research - quantitative diagnostic markers, predictors of outcome, and endophenotypes capable of parsing the heterogeneity of the broader autism spectrum - are also key objectives of the Interagency Autism Coordinating Committee. Project Status
ONGOING

2009

Funder National Institutes of Health
Fiscal Year Funding $584,587.00
Project Number 5R01MH083727-02
Principal Investigator Klin, Ami
Received ARRA Funding? No
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD by 2014. IACC Recommended Budget: $33,300,000 over 5 years.
Federal or Private? Federal
Institution Yale University
State/Country Connecticut
Web Link 1 The ontogeny of social visual engagement in infants at risk for autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects The ontogeny of social visual engagement in infants at risk for autism | $600,325.00 | 2010 | 5R01MH083727-03
The ontogeny of social visual engagement in infants at risk for autism | $580,150.00 | 2008 | R01MH083727-01