Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Pediatric Pharmacology Research Unit  

This grant supports the continuation of the Neonatal and Pediatric Pharmacology Research Unit (PPRU) at the Children's Hospital of Michigan and Wayne State University (WSU). The WSU PPRU has conducted more than 40 multicenter and single site trials of drug therapy for pediatric conditions. Studies on aberrant development of serotonin biosynthesis in autistic children using PET scanning and identification of the phenotypic variants of serotonin metabolism have led to the ongoing evaluation of buspirone in drug therapy of autism. Another current area of focus in developing autism treatments involves targeting brain GABA receptors. Support for this research unit will advance rational, safe, effective and cost beneficial drug therapies in the fetus, newborn, and children. Project Status


Funder National Institutes of Health
Fiscal Year Funding $243,183.00
Project Number 3U10HD037261-10S1
Principal Investigator Lieh-Lai, Mary
Received ARRA Funding? Yes
Strategic Plan Question Not specific to SP Questions: Not specific to Strategic Plan Questions (Other)
Strategic Plan Objective O. Not specific to objectives
Federal or Private? Federal
Institution Wayne State University
State/Country Michigan
Web Link 1 Pediatric Pharmacology Research Unit (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Pediatric pharmacology research unit | $358,400.00 | 2008 | U10HD037261-10