Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Melatonin for sleep in children with autism: Safety, tolerability, and dosing  

Children with neuropsychiatric conditions, such as autism spectrum disorders (ASD), are at high risk for insomnia, and pharmacological treatments for insomnia in this population are acutely needed. Lack of restorative sleep may exacerbate disabling behaviors associated with ASD. Treatments that promote sleep in children with ASD may ameliorate these behaviors as well as strengthen the ability of parents to cope with this disorder and to assist their children in overcoming their disabilities. The long-term objectives are to determine if supplemental melatonin is an effective treatment for insomnia in children with ASD and whether the use of melatonin to treat insomnia improves these children's daytime behaviors and reduces levels of parental stress. Project Status
ONGOING

2009

Funder National Institutes of Health
Fiscal Year Funding $345,401.00
Project Number 5R01HD059253-02
Principal Investigator Malow, Beth
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SA. Support at least three randomized controlled trials that address co-occurring medical conditions associated with ASD by 2010. IACC Recommended Budget: $13,400,000 over 3 years.
Federal or Private? Federal
Institution Vanderbilt University
State/Country Tennessee
Web Link 1 Melatonin for sleep in children with autism: Safety, tolerability, and dosing (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Melatonin for sleep in children with autism: Safety, tolerability, and dosing | $387,141.00 | 2008 | R01HD059253-01A2
Melatonin for sleep in children with autism: Safety, tolerability, and dosing (supplement) | $140,616.00 | 2009 | 3R01HD059253-02S1