Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Using genetically modified mice to explore the neuronal network involved in social recognition  

There is increasing evidence that oxytocin (OT) and arginine-vasopressin (AVP), two neuropeptides released in the brain, play important roles in social behaviors. In this research, Dr. Wagner and colleagues will develop a genetically modified mouse designed to facilitate the study of the OT- and AVP-producing neuronal network. These mice will be invaluable for examining the structure, physiology, and function of the neural networks involving these neurons and will provide new methods for manipulating the viability, activity, and connectivity of these neurons. Dissecting the functions of the OT- and AVP-producing neurons in an animal model will improve our understanding of the neural networks underlying social behaviors and will provide a basis for parallel research in the roles of these networks and neuropeptides in people with autism spectrum disorders (ASD). Project Status
ONGOING

2009

Funder Autism Speaks
Fiscal Year Funding $60,000.00
Project Number 3613
Principal Investigator Wagner, Schlomo
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Private
Institution Haifa University
State/Country Israel
Web Link 1 Using genetically modified mice to explore the neuronal network involved in social recognition (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Using genetically modified mice to explore the neuronal network involved in social recognition | $60,000.00 | 2008 | 3613
Using genetically modified mice to explore the neuronal network involved in social recognition | $60,000.00 | 2010 | 3613