Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Genetics and gene-environment interactions in a Korean epidemiological sample of autism  

Dr. Kim and her colleagues are currently undertaking a large-scale population study effort in Cheonan, South Korea. Their study will take advantage of the ongoing Korean Environmental Studies I and II, which have obtained blood or saliva samples from 10,000 6- to 12-year-old Korean children. Kim's team plans to collect autism phenotype data — from standard behavioral measures such as the Social Responsiveness Scale and Autism Spectrum Screening Questionnaire — as well as DNA from biological samples from all 10,000 children. In a relatively short time (18 to 24 months) the researchers will have assembled a huge repository of autism-related data from a genetically homogeneous cohort; Koreans originate from a single population, and marriage to people of other ethnicities is uncommon. The researchers believe this consistency boosts the statistical power of their data and provides a unique resource for discovering both common and rare genetic variants that cause or increase the risk of autism, understanding how these genes underlie the disorder's clinical traits, assessing the distribution of these traits and variants, and uncovering gene-environment interactions that lead to development of the disorder. Project Status
NEW

2009

Funder Simons Foundation
Fiscal Year Funding $74,692.00
Project Number 137032
Principal Investigator Kim, Young Shin
Received ARRA Funding? No
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 3SC. Initiate efforts to expand existing large case-control and other studies to enhance capabilities for targeted gene – environment research by 2011. IACC Recommended Budget: $27,800,000 over 5 years.
Federal or Private? Private
Institution Yale University
State/Country Connecticut
Web Link 1 Genetics and gene-environment interactions in a Korean epidemiological sample of autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Genetics and gene-environment interactions in a Korean epidemiological sample of autism | $149,354.00 | 2010 | 137032