Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Language processing in children with 22q11 deletion syndrome and autism  

Dr. Ousley's study will focus on children with 22q11 deletion syndrome, which occurs when a small piece of chromosome 22 is missing. The chromosomal defect is associated with language delay and difficulties in phonology and has been strongly linked to autism spectrum disorder (ASD). The study will include three groups: children who have the genetic syndrome but do not have autism, children affected with both the genetic syndrome and autism, and children who have autism with no known genetic cause. The researchers plan to assess elementary-school children twice for short-term changes in their processing of single words, ability to remember words after hearing them, and more complex forms of verbal expression. By comparing the three groups of children, Ousley hopes to learn whether language progression is impaired differently in autistic children with the genetic defect and whether this impairment could be a red flag for autism in other children with the defect. Project Status
ONGOING

2009

Funder Simons Foundation
Fiscal Year Funding $120,000.00
Project Number 89637
Principal Investigator Ousley, Opal
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective New! Green dot: Objective has greater than or equal to the recommended funding. 2SG. Support five studies that associate specific genotypes with functional or structural phenotypes, including behavioral and medical phenotypes (e.g., nonverbal individuals with ASD and those with cognitive impairments) by 2015. IACC Recommended Budget: $22,600,000 over 5 years.
Federal or Private? Private
Institution Emory University
State/Country Georgia
Web Link 1 Language processing in children with 22q11 deletion syndrome and autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Language processing in children with 22q11 deletion syndrome and autism | $30,000.00 | 2010 | 89637
Language processing in children with 22q11 deletion syndrome and autism | $150,000.00 | 2008 | Project number unavailable