Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Development of neural pathways in infants at risk for autism spectrum disorders (supplement)  

Because autism spectrum disorders (ASD) is not diagnosed reliably before the second or third year of life, the best way to investigate development of the disorder involves studying infant siblings of children with ASD (High-Risk infants), who have a significantly increased risk (10- to 20-fold) of developing ASD. This study uses a neurodevelopmental approach and a variety of techniques to identify abnormalities associated with High-Risk ASD infants (ages 6 to 36 months) by tracking their development in comparison to normal infants. Abnormalities in visual processing, motion processing, face processing, and social/emotional processing will be assessed. Standardized tests will also be used to evaluate social, communicative, and cognitive skills. The hope is that these studies will shed light on the neurodevelopmental origins of ASD (and the broader autism phenotype) and aid in early diagnosis of the disorder. Project Status
NEW

2010

Funder National Institutes of Health
Fiscal Year Funding $244,282.00
Current Award Period 2010-2012
Project Number 3R01HD052804-03S1
Principal Investigator Dobkins, Karen
Received ARRA Funding? Yes
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Subcategory Early Signs and Biomarkers
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 1LA. Identify behavioral and biological markers that separately, or in combination, accurately identify, before age 2, one or more subtypes of children at risk for developing ASD, and evaluate whether these risk markers or profiles can improve early identification through heightened developmental monitoring and screening by 2014. IACC Recommended Budget: $33,300,000 over 5 years.
Federal or Private? Federal
Institution University of California, San Diego
State/Country California
Web Link 1 Development of neural pathways in infants at risk for autism spectrum disorders (supplement) (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Development of neural pathways in infants at risk for autism spectrum disorders | $328,313.00 | 2009 | 5R01HD052804-02
Development of neural pathways in infants at risk for autism spectrum disorders | $325,029.00 | 2010 | 5R01HD052804-03
Development of neural pathways in infants at risk for autism spectrum disorders | $328,313.00 | 2008 | R01HD052804-01A2