Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neuroimaging & symptom domains in autism  

Given the heterogeneous nature of autism, identification of homogeneous subgroups is essential to furthering the understanding o f the biology underlying the behaviors associated with this disorder. The availability of noninvasive, non-radioactive neuroimaging techniques and sophisticated data analytic approaches used in combination with family genetic data holds the promise of greatly improving the ability to identify these subgroups. Using these tools, Affected Sibling Pairs selected from the Autism Genetic Resource Exchange multiplex families and a sample of non-autistic control children selected from an ongoing study of normal children at UCLA will be examined. The principal goal of the work proposed in this project is to identify meaningful endophenotypes in autism. These studies will provide the basis for genetic studies to delineate specific gene-brain-behavioral pathways and lay the foundation for early detection and better intervention in autism. Project Status


Funder National Institutes of Health
Fiscal Year Funding $6,078.00
Current Award Period 2010-2011
Project Number 5P41RR013642-13
Principal Investigator Levitt, Jennifer
Received ARRA Funding? No
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Subcategory Intermediate Phenotypes/Subgroups
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.
Federal or Private? Federal
Institution University of California, Los Angeles
State/Country California
Web Link 1 Neuroimaging & symptom domains in autism (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Neuroimaging & symptom domains in autism | $5,153.00 | 2008 | P41RR013642-11