Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

ACE Center: The development of the siblings of children with autism: A longitudinal study  

This grant provides support for an NIH Autism Center of Excellence (ACE). This project is a longitudinal study of over 300 infants at risk for autism based on their family history of having older siblings who are diagnosed with ASD. The developmental trajectories of children from 6 to 36 months will be studied, including subgroups of children who manifest varying patterns of symptoms ranging from full autism to the broader autism phenotype to non-affected siblings. Additionally, the children in this study will be followed to age 5 to describe the developmental trajectory of this cohort more fully. This will enable development of tools for earlier diagnosis and better determination of prognosis. Project Status
ONGOING

2010

Funder National Institutes of Health
Fiscal Year Funding $324,955.00
Current Award Period 2007-2012
Project Number 5P50HD055784-04
Principal Investigator Sigman, Marian
Received ARRA Funding? No
Strategic Plan Question Question 1: When Should I Be Concerned? (Diagnosis)
Subcategory Early Signs and Biomarkers
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 1LB. Develop at least five measures of behavioral and/or biological heterogeneity in children or adults with ASD, beyond variation in intellectual disability, that clearly relate to etiology and risk, treatment response and/or outcome by 2015. IACC Recommended Budget: $71,100,000 over 5 years.
Federal or Private? Federal
Institution University of California, Los Angeles
State/Country California
Web Link 1 ACE Center: The development of the siblings of children with autism: A longitudinal study (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects ACE Center: The development of the siblings of children with autism: A longitudinal study | $331,863.00 | 2009 | 5P50HD055784-03
ACE Center: The development of the siblings of children with autism: A longitudinal study (supplement) | $55,372.00 | 2009 | 3P50HD055784-03S1