Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Pragmatic skills of young males and females with fragile X syndrome (supplement)  

The use of language in social contexts, or pragmatic skills, are essential for daily communication. This study compares the developmental trajectories of these skills. Determining whether a pragmatic skill is either unique to fragile X syndrome (FXS) or related to other conditions, such as gender, mental retardation, or autism, may help in defining treatment options for fragile X in males. In this study, children's pragmatic skills, including their initiations, contingency, perseveration, and repair strategies during conversation and their informativeness and cohesiveness during narration will be assessed annually for four years. Children's language content and structure, cognition, social-emotional behavior (anxiety and autistic characteristics), and family environment will also be examined annually. In addition, Fragile X Mental Retardation Protein (FMRP) analysis from blood samples will be completed on the girls and boys with FXS. These studies may indicate a unique pragmatic phenotype for FXS. Project Status
NEW

2010

Funder National Institutes of Health
Fiscal Year Funding $125,116.00
Current Award Period 2010-2011
Project Number 3R01HD038819-09S1
Principal Investigator Martin, Gary
Received ARRA Funding? Yes
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Developmental Trajectory
Strategic Plan Objective Yellow dot: Objective has some degree of funding, but less than the recommended amount. 2LA. Complete a large-scale, multi-disciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of individuals, with a special emphasis on females, youths, and adults with ASD, change over time as compared to typically developing people by 2020. IACC Recommended Budget: $126,200,000 over 12 years.
Federal or Private? Federal
Institution University of North Carolina at Chapel Hill
State/Country North Carolina
Web Link 1 Pragmatic skills of young males and females with fragile X syndrome (supplement) (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Pragmatic skills of young males and females with fragile X syndrome | $517,519.00 | 2009 | 5R01HD038819-08
Pragmatic skills of young males and females with fragile X syndrome | $507,009.00 | 2010 | 5R01HD038819-09
Pragmatic skills of young males and females with fragile X syndrome | $517,218.00 | 2008 | R01HD038819-07