Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Optical analysis of circuit-level sensory processing in the cerebellum  

Autism spectrum disorders are associated with abnormalities in the cerebellum. Cerebellum function is involved in movement coordination and sensory processing, both of which are dysfunctional in autism. This research project aims to elucidate basic cerebellum function in mice and ultimately its role in coordination. Spontaneous and sensory-evoked activity in populations of cerebellar neurons in anesthetized and alert mice will be recorded using an optical technique that detects neural activity with excellent spatial and temporal resolution. This research will clarify how the basic repeating circuit within the cerebellum processes sensory stimuli and may be relevant to understanding how predictions based on incoming stimuli are stored and represented in the brains of normal and autistic people. Project Status
ONGOING

2010

Funder Autism Speaks
Fiscal Year Funding $48,612.00
Current Award Period 2008-2010
Project Number 2270
Principal Investigator Wang, Samuel
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Sensory and Motor Function
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Private
Institution Princeton University
State/Country New Jersey
Web Link 1 Optical analysis of circuit-level sensory processing in the cerebellum (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Optical analysis of circuit-level sensory processing in the cerebellum | $0.00 | 2009 | 2270
Optical analysis of circuit-level sensory processing in the cerebellum | $49,000.00 | 2008 | 2270