Project Detail
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Office of Autism Research Coordination (OARC) logo

Synaptic analysis of neuroligin1 function  

This is an individual National Research Service Award for post-doctoral research training, which provides support for promising Fellowship Applicants with the potential to become productive, independent investigators in scientific health-related research fields. The overarching goal of this proposal is to explore the mature synaptic function of Neuroligin 1 (NL1), a synapse- specific protein implicated in several autism spectrum disorders (ASDs). Molecular biology and mouse genetics will be used together with synaptic physiology to better understand the normal biological function of NL1 and the possible contributions of mutations in this gene to abnormal synaptic function in neuropsychiatric disorders. In addition to providing potential model systems for the study of ASDs, results from this work will contribute significantly to the limited understanding of NL function at mature synapses. In doing so, they may provide new targets for future molecular interventions in psychiatric disorders. Project Status
ONGOING

2010

Funder National Institutes of Health
Fiscal Year Funding $52,154.00
Current Award Period 2009-2011
Project Number 5F32MH086176-02
Principal Investigator Fuccillo, Marc
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Molecular Pathways
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Federal
Institution Stanford University
State/Country California
Web Link 1 Synaptic analysis of neuroligin1 function (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Not available at this time. This functionality is experimental.