Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

A primate model of gut, immune, and CNS response to childhood vaccines  

Diagnoses of childhood developmental disorders involving autism-spectrum symptoms are increasing, estimated to affect 1 in 100 children in the United States. Childhood vaccines have been hypothesized to be contributory factors to this increase. The childhood vaccine regimen has an experimentally unstudied potential for cumulative and synergistic toxicities and possible immunologic interference to normal development. Project Status
ONGOING

2010

Funder National Institutes of Health
Fiscal Year Funding $155,086.00
Current Award Period 2009-2011
Project Number 5P51RR000166-49
Principal Investigator Sackett, Gene
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Immune/Metabolic Pathways
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 2SA. Support at least four research projects to identify mechanisms of fever, metabolic and/or immune system interactions with the central nervous system that may influence ASD during prenatal-postnatal life by 2010. IACC Recommended Budget: $9,800,000 over 4 years. (Fever studies to be started by 2012.)
Federal or Private? Federal
Institution University of Washington
State/Country Washington
Web Link 1 A primate model of gut, immune, and CNS response to childhood vaccines (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
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