Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

ACE Center: Genetics of language & social communication: Connecting genes to brain & cognition  

This grant provides support for an NIH Autism Center of Excellence (ACE). Research from several groups suggests that studying cognitive or behavioral components of autism, or endophenotypes, may aid in identification of more homogeneous subgroups and hasten the identification of genetic loci underlying this condition. This study tests the hypothesis that speech and language related endophenotypes may underlie several of the suggestive or probable autism linkage peaks. The research uses the Autism Genetic Resource Exchange (AGRE) to identify one major and several minor linkage peaks related to speech and language delay in autistic siblings in this large autism cohort (AGRE). Project Status
ONGOING

2010

Funder National Institutes of Health
Fiscal Year Funding $325,302.00
Current Award Period 2007-2012
Project Number 5P50HD055784-04
Principal Investigator Geschwind, Daniel
Received ARRA Funding? No
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Subcategory Subgroups/Biosignatures
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 2SG. Support five studies that associate specific genotypes with functional or structural phenotypes, including behavioral and medical phenotypes (e.g., nonverbal individuals with ASD and those with cognitive impairments) by 2015. IACC Recommended Budget: $22,600,000 over 5 years.
Federal or Private? Federal
Institution University of California, Los Angeles
State/Country California
Web Link 1 ACE Center: Genetics of language & social communication: Connecting genes to brain & cognition (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects ACE Center: Genetics of language & social communication: Connecting genes to brain & cognition | $333,180.00 | 2009 | 5P50HD055784-03
ACE Center: Genetics of language & social communication: Connecting genes to brain & cognition (supplement) | $55,592.00 | 2009 | 3P50HD055784-03S1