Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Methods for production of ICSI and SCNT derived macaque stem cells  

While human embryonic stem cells may have incredible therapeutic value for treating a wide range of disorders such as Parkinson's diabetes, autism, heart disease, Alzheimer's etc., rigorous testing in animal models is necessary before any such trials can begin. With this grant, researchers will develop and refine methods for producing viable embryonic stem cells from macaque monkeys. In this pilot project, researchers seek to determine whether or not macaque monkeys may be an ideal animal model for future work. Any established cell lines will undergo rigorous testing to determine their pluripotency and normalcy. Macaques provide a valuable non-human primate model in which to determine the safety and efficacy of stem cells. Project Status
ONGOING

2010

Funder National Institutes of Health
Fiscal Year Funding $19,188.00
Current Award Period 2009-2012
Project Number 5P51RR013986-12
Principal Investigator Schatten, Gerald
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Treatments)
Subcategory Model Systems/Therapeutic Targets
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution Southwest Foundation For Biomedical Research
State/Country Texas
Web Link 1 Methods for production of ICSI and SCNT derived macaque stem cells (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
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