Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD  

Previous work from the Tierney laboratory has suggested that some individuals with autism spectrum disorders (ASDs) have very low blood cholesterol levels. Low cholesterol may be an important marker for subtypes of ASD; it may also play a role in causing some types of ASD, as cholesterol is known to be important for several aspects of brain development. The present study will test the response of individuals with ASD and low cholesterol to increased cholesterol in their diets. A randomized sample of youths with ASD will be given supplementary cholesterol over a 12 week period, and the effects of the treatment on behavior, communication, and other features of autism will be measured and compared to a group given placebo. This research will help to determine whether adding cholesterol to the diet can improve behavioral problems seen in individuals with ASD and low cholesterol. Project Status
ONGOING

2010

Funder Autism Speaks
Fiscal Year Funding $200,000.00
Current Award Period 2008-2011
Project Number 2990
Principal Investigator Tierney, Elaine
Received ARRA Funding? No
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Treatments)
Subcategory Complementary, Dietary, and Alternative
Strategic Plan Objective Yellow dot: Objective has some degree of funding, but less than the recommended amount. 4SC. Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012. IACC Recommended Budget: $27,800,000 over 5 years.
Federal or Private? Private
Institution Kennedy Krieger Institute
State/Country Maryland
Web Link 1 Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD (External web link)
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD | $100,000.00 | 2009 | 2990
Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD | $300,000.00 | 2008 | 2990