Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

A longitudinal MRI study of infants at risk for autism  

Multiple lines of converging evidence (from magnetic resonance imaging (MRI), post-mortem, and head circumference studies) document brain enlargement in autism. New methods of imaging, image processing and behavioural assessment are used to conduct a longitudinal MRI/DTI study of six months old infant sibs of autistic individuals, with follow-up at 12 and 24 months of age. This study will provide important new information about the trajectory of early postnatal brain overgrowth and its potential relationship to clinical features.

2008

Funder National Institutes of Health
Fiscal Year Funding $2,726,522.00
Project Number R01HD055741-02
Principal Investigator Piven, Joseph
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective Yellow dot: Objective has some degree of funding, but less than the recommended amount. 2.5 Complete a large-scale, multi-disciplinary, collaborative project that longitudinally and comprehensively examines how the biological, clinical, and developmental profiles of children, with a special emphasis on females, youths, and adults with ASD change over time as compared to typically developing people by 2020. IACC Recommended Budget: $126,200,000 over 12 years.
Federal or Private? Federal
Institution University of North Carolina at Chapel Hill
State/Country North Carolina
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects A longitudinal MRI study of infants at risk for autism- Supplemental | $622,534.00 | 2008 | R01HD055741-02S1A1
ACE Network: A longitudinal MRI study of infants at risk for autism | $3,283,233.00 | 2010 | 5R01HD055741-04
ACE Network: A longitudinal MRI study of infants at risk for autism | $3,317,464.00 | 2009 | 5R01HD055741-03