Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Proteomics in Drosophila to identify autism candidate substrates of UBE3A  

The primary goal of this research is to identify proteins regulated by UBE3A and to investigate the possibility that these proteins are also dysregulated or mutated in some cases of autism. Understanding how increased levels of UBE3A result in an autism phenotype at the molecular level will help to better identify and treat the underlying liability in idopathic autism.

2008

Funder National Institutes of Health
Fiscal Year Funding $313,338.00
Project Number R01NS059902-01A2
Principal Investigator Reiter, Lawrence
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 3.8 Identify genetic risk factors in at least 50% of people with ASD by 2014. IACC Recommended Budget: $33,900,000 over 6 years.
Federal or Private? Federal
Institution University of Tennessee Health Science Center
State/Country Tennessee
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Proteomics in Drosophila to identify autism candidate substrates of UBE3A | $319,550.00 | 2009 | 5R01NS059902-02
Proteomics in Drosophila to identify autism candidate substrates of UBE3A (supplement) | $10,000.00 | 2009 | 3R01NS059902-02S1
Proteomics in drosophila to identify autism candidate substrates of UBE3A | $316,355.00 | 2010 | 5R01NS059902-03