Project Detail
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Mechanisms for 5-HTT control of PPI and perseverative behavior using mouse models  

This study will use behavioral and genetic mouse models to identify the neural mechanisms by which serotonin transporter (5-HTT) function modulates sensorimotor gating deficits and perseverative behaviors. Sensorimotor gating is a neural mechanism that filters excessive sensory, cognitive, and motor information, permitting mental and behavioral integration. This unique approach could lead to novel animal models of the sensorimotor gating deficits and perseverative behaviors in obsessive compulsive disorder and autism.

2008

Funder National Institutes of Health
Fiscal Year Funding $345,375.00
Project Number R01MH079424-02
Principal Investigator Dulawa, Stephanie
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective 3O. Not specific to Question 3 objectives
Federal or Private? Federal
Institution University of Chicago
State/Country Illinois
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Mechanisms for 5-HTT control of PPI and perseverative behavior using mouse models | $345,375.00 | 2009 | 5R01MH079424-03
Mechanisms for 5-HTT control of PPI and perseverative behavior using mouse models | $387,353.00 | 2010 | 5R01MH079424-04
Mechanisms for 5-HTT control of PPI and perseverative behavior using mouse models (supplement) | $6,802.00 | 2010 | 3R01MH079424-03S2