Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Treatment of medical conditions among individuals with autism spectrum disorders  

This study is conducting a single arm, open-label clinical trial of donepezil hydrochloride to evaluate its ability to enhance REM sleep in children with autism who exhibit a low abnormally short time in the REM sleep stage of sleep (defined as below 2 standard deviations of observed normative data for age). If REM sleep is necessary for normal cognition and its deficiency or absence can be remedied by pharmacologic intervention, then it may follow that improvement of REM sleep correlates with improved short and long term cognition in children with autism.

2008

Funder National Institutes of Health
Fiscal Year Funding $465,840.00
Project Number Z01MH002914-01
Principal Investigator Swedo, Susan
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective 4O. Not specific to Question 4 objectives
Federal or Private? Federal
Institution National Institutes of Health
State/Country Maryland
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Treatment of medical conditions among individuals with autism spectrum disorders | $535,209.00 | 2009 | 1ZIAMH002914-02
Treatment of medical conditions among individuals with autism spectrum disorders | $578,006.00 | 2010 | 1ZIAMH002914-03