Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neuropathology$2,353,294.00
Fiscal Year: 2010
  

Download 2010 Neuropathology projects (EXCEL)
These projects typically include post-mortem examination of brain tissue from ASD individuals. Many of the studies in this subcategory explore how the architecture of the brain may be altered in individuals with autism or how gene expression varies in different areas of the brain.
Graph: Question 2 encompassed a broad range of biological research, resulting in the need to create a larger number of subcategories to adequately describe the breadth of research than was required for other Strategic Plan Questions. The subcategory with the largest portion of funding was Molecular pathways (32%), followed by Neural systems and Subgroups/Biosignatures, which each received less than half the funding of Molecular pathways (15% and 14%, respectively). Projects related to Developmental trajectory were supported by 11% of 2010 ASD research funding, and research on Sensory and motor function received 7%. Studies on Immune/Metabolic pathways (6%), Co-occurring conditions (5%), Cognitive studies (5%), and Computational science (4%) round out the types of research in Question 2.
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
RNA-Seq studies of gene expression in cells and networks in FI and ACC in autism Allman, John; Wold, Barbara Q2.Other California Institute of Technology
Architecture of myelinated axons linking frontal cortical areas Barbas, Helen Q2.Other Boston University
Olivocerebellar circuitry in autism Blatt, Gene Q2.Other Boston University Medical Campus
Gross morphological correlates to the minicolumnopathy of autism Casanova, Manuel Q2.Other University of Louisville
Characterization of the pathological and biochemical markers that correlate to the clinical features of autism Chauhan, Abha Q2.Other Research Foundation for Mental Hygiene, Inc.
ACE Center: Diffusion tensor MRI + histopathology of brain microstructure + fiber pathways Conturo, Thomas Q2.Other University of Pittsburgh
Gene expression and laminar analyses of pathological cortical patches in autism Courchesne, Eric Q2.Other University of California, San Diego
Stereological analyses of neuron numbers in frontal cortex from age 3 years to adulthood in autism Courchesne, Eric Q2.Other University of California, San Diego
Dendritic organization within the cerebral cortex in autism Gabbott, Paul; Rezaie, Payam Q2.Other The Open University
Cerebellar modulation of frontal cortical function Mittleman, Guy; Blaha, Charles; Goldowitz, Daniel; Heck, Detlef Q2.Other University of Memphis
Characterization of the pathological and biochemical markers that correlate to the clinical features of autism Wegiel, Jerzy Q2.Other Research Foundation for Mental Hygiene, Inc.
Characterization of the pathological and biochemical markers that correlate to the clinical features of autism Wisniewski, Thomas Q2.Other Research Foundation for Mental Hygiene, Inc.
Enhanced tissue procurement from autistic indivdiuals Zielke, H.Ronald Q2.S.C NICHD (National Institute of Child Health & Human Development) Brain and Tissue Bank for Developmental Disorders, University of Maryland