Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Model Systems/Therapeutic Targets$24,115,793.04
Fiscal Year: 2010
  

Download 2010 Model Systems/Therapeutic Targets projects (EXCEL)
Animal models mimicking behaviors of ASD and those that are being used to develop or test new drug treatments, as well as cell lines used to discover new drug targets or to screen potential drug candidates, are included in this subcategory.
Graph: The subcategories for Question 4 illustrate the many approaches to treatments and interventions supported by autism research funders. The largest amount of funding supported projects to develop Model systems and therapeutic targets (35%), followed by research on Behavioral interventions (29%). Medical/Pharmacologic interventions received 16% of funding, classroom-based interventions (Educational) received 10% of funding, and Technology-based interventions and supports received 7% of funding. The subcategories with the smallest amounts of funding included Occupational, physical, and sensory-based (2%) and Complementary, dietary, and alternative (1%).
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
Analysis of cortical circuits related to ASD gene candidates Zador, Anthony Q4.S.B Cold Spring Harbor Laboratory
Regulation of gene expression in the brain Young, Walter Q4.S.B National Institutes of Health
Genomic resources for identifying genes regulating social behavior Young, Larry Q4.S.B Emory University
Vasopressin receptors and social attachment Young, Larry Q4.S.B Emory University
Neural mechanisms of social cognition and bonding Young, Larry Q4.S.B Emory University
Neural mechanisms of social cognition and bonding Young, Larry Q4.S.B Emory University
Central vasopressin receptors and affiliation Young, Larry Q4.S.B Emory University
Central vasopressin receptors and affiliation Young, Larry Q4.S.B Emory University
Basal ganglia circuitry and molecules in pathogenesis of motor stereotypy Yang, Xiangdong Q4.S.B University of California, Los Angeles
Dynamic regulation of Shank3 and ASD Worley, Paul Q4.S.B Johns Hopkins University
Cntnap2 in a behavioral model of autism White, Stephanie Q4.S.B University of California, Los Angeles
Mouse genetic model of a dysregulated serotonin transporter variant associated with autism Veenstra-Vanderweele, Jeremy Q4.S.B Vanderbilt University
Murine genetic models of autism Veenstra-Vanderweele, Jeremy Q4.S.B Vanderbilt University
Integrated approach to the neurobiology of autism spectrum disorders Vaccarino, Flora Q4.S.B Yale University
Cellular and genetic correlates of increased head size in autism spectrum disorder Vaccarino, Flora Q4.S.B Yale University
Characterization of the transcriptome in an emerging model for social behavior Thomas, James Q4.S.B Emory University
Neural and cognitive mechanisms of autism Sur, Mriganka Q4.S.B Massachusetts Institute of Technology
Function and dysfunction of neuroligins Sudhof, Thomas Q4.S.B Stanford University
Identifying impairments in synaptic connectivity in mouse models of ASD Speed, Haley Q4.S.B University of Texas Southwestern Medical Center
Characterization of autism susceptibility genes on chromosome 15q11-13 Smith, Stephen Q4.S.B Beth Israel Deaconess Medical Center
Using zebrafish and chemical screening to define function of autism genes Sive, Hazel Q4.S.B Whitehead Institute for Biomedical Research
Mice lacking Shank postsynaptic scaffolds as an animal model of autism Sheng, Morgan Q4.S.B Massachusetts Institute of Technology
Dissecting the neural control of social attachment Shah, Nirao Q4.S.B University of California, San Francisco
Novel, subtype selective potentiators of nicotinic acetycholine receptors Schulte, Marvin Q4.Other University of Alaska Fairbanks
Methods for production of ICSI and SCNT derived macaque stem cells Schatten, Gerald Q4.S.B Southwest Foundation For Biomedical Research