Subcategory Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Epigenetics$5,540,146.28
Fiscal Year: 2010
  

Download 2010 Epigenetics projects (EXCEL)
Epigenetics is the study of heritable changes in gene function that occur without a change in the DNA sequence (such as methylation of DNA). Environmental factors can cause these changes in gene expression, and projects in this subcategory seek to identify some of the environmental influences that may lead to these epigenetic changes.
Graph: Genetic risk factors accounted for a majority of research funding in Question 3 in 2010 (63%). Gene-Environment studies received 25% of funding, Epigenetic studies 7%, and Environment studies 5%.
Note: Initial Sort is by Principal Investigator. Sorting by other columns is available by clicking on the desired column header.
Project Title Principal Investigator Strategic Plan Objective Institution
In vivo function of neuronal activity-induced MeCP2 phosphorylation Chang, Qiang Q3.S.J University of Wisconsin - Madison
Sex chromosomes, epigenetics, and neurobehavioral disease Rissman, Emilie Q3.S.K University of Virginia
Epigenetics, hormones and sex differences in autism incidence Rissman, Emile Q3.S.K University of Virginia
Epigenetic regulation of the autism susceptibility gene, ENGRAILED 2 (EN2) Millonig, James Q3.S.J University of Medicine & Dentistry of New Jersey - Robert Wood Johnson Medical School
Toxicant-induced autism and mitochondrial modulation of nuclear gene expression Wlodarczyk, Bogdan Q3.S.J Texas A&M University
Identification of aberrantly methylated genes in autism: The role of advanced paternal age Gingrich, Jay Q3.S.J Research Foundation for Mental Hygiene, Inc.
Genome-wide analyses of DNA methylation in autism Chess, Andrew Q3.S.J Massachusetts General Hospital
Identical twins discordant for autism: Epigenetic (DNA methylation) biomarkers of non-shared environmental influences Plomin, Robert Q3.S.J King's College London
Discordant monozygotic twins as a model for genetic-environmental interaction in autism Kaufmann, Walter Q3.S.J Kennedy Krieger Institute
Environment, the perinatal epigenome, and risk for autism and related disorders Fallin, Margaret; Feinberg, Andrew Q3.S.J Johns Hopkins University
Discordant monozygotic twins as a model for genetic-environmental interaction in autism Feinberg, Andrew Q3.S.J Johns Hopkins University
Epigenetic marks as peripheral biomarkers of autism Warren, Stephen Q3.S.J Emory University
DNA methylation and other epigenetic studies of autism brain Beaudet, Arthur Q3.S.J Baylor College of Medicine
The role of the Rett gene, chromosome 15q11-q13, other genes, and epigenetics Beaudet, Arthur Q3.S.J Baylor College of Medicine
Human neurobehavioral phenotypes associates with the extended PWS/AS domain Beaudet, Arthur Q3.S.J Baylor College of Medicine
Studies of postmortem brain searching for epigenetic defects causing autism Beaudet, Arthur Q3.S.J Baylor College of Medicine
Maternal supplementation of folic acid and function of autism gene synaptic protein Shank3 in animal model Jiang, Yong-Hui Q3.S.J Baylor College of Medicine